Description
Our Honokiol is a magnolia bark lignan, supplied for lab research. It’s tested to 99% purity or higher and sold strictly for lab research.
What is Honokiol?
Honokiol is a lignan from the bark of Magnolia officinalis and other magnolias. Ours is 98% pure.
Magnolia bark has a long history in Chinese and Japanese medicine for anxiety and sleep.
How it works
Honokiol enhances GABA-A receptor activity, which explains its calming effects in animals. It also activates SIRT3 in mitochondria and blocks several cancer signaling pathways in culture.
It crosses into the brain easily.
Honokiol research
Lab studies report anti-anxiety, anti-inflammatory and anticancer effects. Pillai and colleagues reported in 2015 that honokiol activated SIRT3 and protected mouse hearts from enlargement.
Human data are limited to magnolia bark extracts.
To read the original papers, start with this PubMed search for Honokiol.
Choosing your option
There are 2 ways to buy it, from $22.93 to $37.71:
- 5g: $22.93
- 10g: $37.71
Using Honokiol in the lab
Plant extracts contain many compounds, so a common design compares the whole extract with its main isolated compound to see which effects come from which.
Write the extract ratio or standardization into your methods. It’s the detail reviewers ask about first.
Endpoints depend on the plant: immune markers and cytokines for mushroom beta-glucans, glucose and lipids for metabolic botanicals, or behavior tests for calming plants.
Honokiol product details
- Compound: Honokiol
- Also known as: magnolia bark extract
- CAS number: 35354-74-6
- Molecular formula: C18H18O2
- Molar mass: 266.3 g/mol
- Structure: biphenyl lignan
- Class: magnolia bark lignan
- Options: 2 sizes and forms
- Purity: 99% or higher, verified by first- and third-party testing
- Use: laboratory research only
Purity and batch testing
We test each batch for identity and purity before it ships, using HPLC and mass spectrometry, with independent third-party checks on top of our own.
The batch number on the label matches the certificate of analysis. If your lab keeps paperwork on file, ask us for it and we’ll email it over.
How to store Honokiol
Keep the container sealed at room temperature, away from heat, moisture and sunlight. Write the date you opened or mixed it on the label, so anyone else in the lab knows how old it is.
Working with it safely
Treat it as a lab chemical. Gloves and safety glasses are the minimum, and a clean, uncluttered workspace cuts down on mix-ups.
Store prepared solutions apart from untouched stock, and record who mixed what and when.
Often ordered alongside
- Oroxylin A: Oroxylin A is a flavone from Scutellaria baicalensis root and Oroxylum indicum bark.
- Sea Moss: Sea Moss gummies have organic Irish sea moss (2,400mg), bladderwrack (1,500mg) and burdock root (360mg) per serving, at about 20 calories.
- Mucuna Pruriens 98% L-Dopa: Mucuna pruriens is velvet bean, a tropical legume whose seeds are naturally rich in L-dopa, the precursor to dopamine.
- Shroomz: Shroomz is a blend of five mushroom materials, including lion’s mane, cordyceps, shiitake and maitake, standardized for research.
- Blue Lotus 30:1: Blue lotus is Nymphaea caerulea, a water lily from the Nile that shows up often in ancient Egyptian art.
For the wider range, visit our botanical extracts and mushrooms sections.
Similar compounds compared
C3G (Cyanidin 3 Glucoside): C3G, cyanidin-3-glucoside, is the most common anthocyanin in nature, found in blackberries, black rice, bilberries and purple corn.
Cordyceps Sinensis: Cordyceps sinensis is a fungus that grows on caterpillar larvae in the Tibetan plateau. Wild material is rare and costly, so most products are cultured mycelium.
Honokiol questions
How should I store it?
Follow the storage section above. In short: cold and dark for freeze-dried vials, room temperature and dry for capsules, tablets, powders and liquids, unless the label says otherwise.
What forms does it come in?
It comes in 2 sizes, listed in the dropdown on this page.
Is Honokiol in stock?
Yes. It’s in stock and ships from our warehouse after your order clears.
Does it come with a certificate of analysis?
Yes. Every batch is tested, and we’ll email the certificate of analysis for your batch number on request.
Can it be used in people or animals?
No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.
Buy Honokiol from Pure Rawz
Honokiol is in stock from $22.93. Choose your option, add it to the cart and check out in a couple of minutes.
Need more for the same project? Have a look at our botanical extracts and mushrooms.
For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.






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