Description
Our RAD-140 is a nonsteroidal selective androgen receptor modulator (SARM), supplied as capsules, tablets, a liquid, a powder and an injectable solution. It’s tested to 99% purity or higher and sold strictly for lab research.
RAD-140 explained
RAD-140 (testolone, also called vosilasarm) is a nonsteroidal SARM developed by Radius Health. In preclinical work it showed strong activity in muscle with much less effect on the prostate and seminal vesicles than testosterone.
Radius later studied it in breast cancer, where it acts on androgen receptors in tumor cells. It isn’t an approved medicine.
Mechanism of action
RAD-140 binds the androgen receptor and drives androgen-responsive gene activity in muscle and bone, with partial activity in the prostate. In monkeys it raised lean mass at exposures that left prostate size mostly unchanged.
In ER-positive breast cancer cells, switching on the androgen receptor holds back estrogen-driven growth, which is why Radius tested it there. Rodent work also suggested it protects neurons in culture.
Published RAD-140 research
The founding paper is Miller and colleagues, ACS Medicinal Chemistry Letters, 2011, which described RAD-140’s discovery and its tissue selectivity in rats and monkeys.
A phase 1 trial in women with advanced ER-positive, HER2-negative breast cancer reported its pharmacokinetics and side effects, including liver enzyme rises in some patients.
The primary literature is on PubMed. Here’s a search to start from.
RAD-140 sizes and forms
It comes in 9 options. Pick one from the dropdown above the cart button:
- Capsules, 20mg/60ct/1.2g: $202.81
- Tablets, 20mg/27ct/540mg: $91.26
- Tablets, 20mg/54ct/1080mg: $182.54
- Liquid, 15ml/17mg per ml/250mg: $42.25
- Liquid, 30ml/17mg per ml/500mg: $84.51
- Liquid, 30ml/33mg per ml/1000mg: $169.02
- Liquid, 30ml/67mg per ml/2000mg: $338.03
- Powder, 1g: $169.02
- Injectable, 10ml/64mg per ml/640mg: $108.17
Capsules hold a measured amount each, listed in the size option with the count and total.
Each tablet holds the same measured amount, which the size option spells out.
The liquid comes in a glass dropper bottle at a stated concentration per mL, so every draw is easy to calculate.
The powder is the bulk form, for labs that weigh their own amounts. Use a milligram scale for accuracy.
The injectable form is a sterile solution in a sealed vial at a stated concentration per mL.
Study design notes
Labs comparing SARMs usually match exposure time and measure the same panel across compounds: muscle and prostate weight in rodents, plus hormone and lipid markers. That tissue-selectivity ratio is what SARM research is built around.
Liquids make small, even measurements easy, while capsules and tablets suit studies that need a fixed amount per unit.
The classic rodent readout compares levator ani muscle weight with prostate weight, which shows how tissue-selective a compound is. Body composition scans and hormone blood work usually sit alongside it.
Measuring the liquid
At 17mg per mL, every 1mL holds 17mg and every 0.1mL holds 1.7mg. A graduated 1mL dropper or syringe makes those measures accurate.
RAD-140 product details
- Compound: RAD-140
- Also known as: testolone, vosilasarm
- CAS number: 1182367-47-0
- Molecular formula: C20H16ClN5O2
- Molar mass: 393.8 g/mol
- Structure: nonsteroidal benzonitrile with an oxadiazole ring
- Class: nonsteroidal selective androgen receptor modulator (SARM)
- Forms: capsules, tablets, liquid, powder and injectable
- Options: 9 sizes and forms
- Purity: 99% or higher, verified by first- and third-party testing
- Use: laboratory research only
Purity and batch testing
We test each batch for identity and purity before it ships, using HPLC and mass spectrometry, with independent third-party checks on top of our own.
The batch number on the label matches the certificate of analysis. If your lab keeps paperwork on file, ask us for it and we’ll email it over.
How to store RAD-140
Keep the container sealed at room temperature, away from heat, moisture and sunlight. Keep the bottle capped, upright and out of direct sunlight at room temperature unless the label says otherwise.
Note the batch number and the date you opened it in your lab records.
Working with it safely
Handle it the way you’d handle any research chemical: gloves, eye protection and a clean bench. Don’t eat or drink where you work with it.
Keep it out of reach of anyone who isn’t trained, and dispose of used syringes, vials and wipes according to your lab’s waste rules.
Before you start
- a graduated 1mL dropper or syringe for accurate volumes
- a milligram scale, since powder has to be weighed
- a suitable solvent if you’re making your own solution, such as DMSO or propylene glycol
Related products
- Sculptor SARM Stack (Ostarine + Andarine S4), combining MK-2866 and S4 Andarine
- SARM Transdermal Stack (S-23 + YK-11 + LGD-4033 + Laxogenin), combining S-23, YK-11, LGD-4033 and Laxogenin
- Olympian Quad Capsules: Olympian Quad puts four compounds in one capsule: arimistane 40mg, 1-Andro 80mg, 4-Andro 80mg and MK-677 40mg, for 240mg per capsule and 30 capsules per bottle.
- RAD-150 (TLB 150): RAD-150 (also sold as TLB-150) is an ester of RAD-140.
- Andarine (S-4): S4 (andarine, also GTx-007) is one of the first nonsteroidal SARMs, developed by GTx Inc. alongside ostarine.
For the wider range, visit our SARMs sections.
RAD-140 FAQ
Is RAD-140 in stock?
Yes. It’s in stock and ships from our warehouse after your order clears.
Does it come with a certificate of analysis?
Yes. Every batch is tested, and we’ll email the certificate of analysis for your batch number on request.
Can it be used in people or animals?
No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.
How should I store it?
Follow the storage section above. In short: cold and dark for freeze-dried vials, room temperature and dry for capsules, tablets, powders and liquids, unless the label says otherwise.
What forms does it come in?
Capsules, tablets, a liquid, a powder and an injectable solution. Pick the one you want from the dropdown on this page.
Order RAD-140 today
Order RAD-140 now from $42.25. It’s in stock, and checkout takes about two minutes.
Need more for the same project? Have a look at our SARMs.
For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.
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