GHRP-2 (Pralmorelin)

Description

Pure Rawz GHRP-2 is a synthetic growth hormone releasing hexapeptide, available as freeze-dried vials. Every batch is tested for 99% purity or better, and it’s sold for laboratory research only.

What is GHRP-2?

GHRP-2 (pralmorelin) is a six-amino-acid synthetic peptide that acts on the ghrelin receptor and makes the pituitary release growth hormone. It came out of the growth hormone releasing peptide program started by Cyril Bowers at Tulane University.

Compared with GHRP-6 it releases more GH for the same amount and has a smaller effect on appetite, though it still raises cortisol and prolactin a little. In Japan it’s approved as a diagnostic agent for testing GH deficiency.

How it works

GHRP-2 binds GHS-R1a, the receptor that ghrelin uses. In the pituitary that triggers GH release, and in the hypothalamus it adds to the GHRH signal and damps somatostatin, the hormone that holds GH back.

Because GHRP-2 and GHRH push on two different receptors, labs often combine them. The result is a GH pulse larger than the sum of each one on its own, which is the idea behind our CJC-1295 and GHRP-2 blend.

What studies say about GHRP-2

Bowers and colleagues published a series of human studies in the 1990s showing that GHRP-2 raised GH in a dose-related way, and that giving it with GHRH produced a much bigger GH pulse than either one alone.

Later work used it to test pituitary GH reserve and looked at its effects on appetite and food intake, which are milder than with GHRP-6.

The primary literature is on PubMed. Here’s a search to start from.

GHRP-2 sizes and forms

This listing is a single 10mg freeze-dried vial for $42.50.

The vials hold a freeze-dried (lyophilized) powder under a sealed stopper. Freeze-drying keeps the peptide stable in transit. You add sterile bacteriostatic water to dissolve it before use.

How labs use it

Growth hormone research usually measures GH pulses and IGF-1 in blood, and sometimes body composition. Because GH comes in pulses, sampling time matters a lot.

Many labs pair a GHRH-type peptide with a ghrelin-receptor peptide to study how the two signals add up. Fasting state and time of day both change GH output, so keep them constant between groups.

Freeze-dried peptides are easy to store, so ordering enough for a full study at once keeps every group on the same batch.

Mixing and concentration

The liquid you add sets the concentration. For a 10mg vial:

• 1mL of bacteriostatic water gives 10mg/mL
• 2mL of bacteriostatic water gives 5mg/mL
• 3mL of bacteriostatic water gives 3.33mg/mL

Add the water slowly along the inside of the vial and roll it gently until the powder dissolves. Shaking can damage peptide chains.

GHRP-2 at a glance

• Compound: GHRP-2
• Also known as: pralmorelin
• CAS number: 158861-67-7
• Molecular formula: C45H55N9O6
• Molar mass: 817.9 g/mol
• Structure: D-Ala-D-2Nal-Ala-Trp-D-Phe-Lys-NH2
• Class: synthetic growth hormone releasing hexapeptide
• Forms: peptide vial
• Size: 10mg
• Purity: 99% or higher, verified by first- and third-party testing
• Use: laboratory research only

Purity and batch testing

Every batch is tested before it goes on sale. Identity is checked by mass spectrometry, and purity by HPLC, with a target of 99% or higher.

Each container is labeled with the product, the amount and the batch number. Email us that number and we’ll send the certificate of analysis for your batch.

Storage and shelf life

Keep sealed vials in a freezer at -20°C or a fridge at 2 to 8°C, away from light. After mixing, store the vial in the fridge and use it within about four weeks. Note the batch number and the date you opened it in your lab records.

Handling notes

Wear gloves and eye protection when you open or measure it, and work on a clean surface.

Label everything you prepare, keep it away from food areas, and follow your lab’s rules for disposing of sharps and chemical waste.

Before you start

• Bacteriostatic Water for reconstitution, or Sterile Water if you’ll use the whole vial at once
• sterile insulin-type syringes or pipettes for measuring
• alcohol swabs for the vial stopper

Other compounds to look at

• KP-102: KP-102 is the development code for pralmorelin, the peptide better known as GHRP-2.
• Mod GRF 1-29 (CJC-1295 No Dac): CJC-1295 without DAC, also called modified GRF(1-29), is GHRH(1-29) with four amino acid changes that protect it from enzymes.
• ACE-031: ACE-031 (ramatercept) is a fusion protein of the activin receptor type IIB and an antibody Fc fragment.
• MK-677 + Zinc + 5-HTP + Vitamin B6 + TUDCA Capsules, combining MK-677, 5-HTP, B-6 and TUDCA
• Ipamorelin: Ipamorelin is a pentapeptide growth hormone secretagogue developed by Novo Nordisk.

You can also browse our full growth hormone peptides pages.

GHRP-2 questions

Is GHRP-2 in stock?

Yes. It’s in stock and ships from our warehouse after your order clears.

Does it come with a certificate of analysis?

Yes. Every batch is tested, and we’ll email the certificate of analysis for your batch number on request.

Can it be used in people or animals?

No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.

What do I mix it with?

Most labs use sterile bacteriostatic water. Add it slowly down the side of the vial and swirl gently until the powder dissolves. Don’t shake it.

How should I store it?

Follow the storage section above. In short: cold and dark for freeze-dried vials, room temperature and dry for capsules, tablets, powders and liquids, unless the label says otherwise.

Buy GHRP-2 from Pure Rawz

GHRP-2 is in stock at $42.50. Add it to the cart and check out in a couple of minutes.

Need more for the same project? Have a look at our growth hormone peptides and research peptides.

For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.