ACE-031

Description

ACE-031 is a soluble activin receptor fusion protein, sold by Pure Rawz for laboratory research. Each batch is checked for 99%+ purity. It’s intended for research use only.

What is ACE-031?

ACE-031 (ramatercept) is a fusion protein of the activin receptor type IIB and an antibody Fc fragment. It soaks up myostatin and related ligands.

Acceleron developed it for Duchenne muscular dystrophy.

How it acts in research models

ACE-031 is the ligand-binding part of the ActRIIB receptor fused to an antibody Fc tail. It soaks up myostatin, activin and GDF-11 before they reach muscle receptors.

With those growth brakes removed, muscle grows. Because it also binds other ligands, it caused small bleeding problems in its clinical trial.

Published ACE-031 research

A trial in boys with Duchenne was stopped early because of nosebleeds and small blood vessel problems.

Earlier healthy volunteer studies reported increases in muscle volume.

To read the original papers, start with this PubMed search for ACE-031.

Options and prices

This listing is a single 1mg size, priced at $162.31.

Study design notes

Growth hormone research usually measures GH pulses and IGF-1 in blood, and sometimes body composition. Because GH comes in pulses, sampling time matters a lot.

Many labs pair a GHRH-type peptide with a ghrelin-receptor peptide to study how the two signals add up. Fasting state and time of day both change GH output, so keep them constant between groups.

Freeze-dried peptides are easy to store, so ordering enough for a full study at once keeps every group on the same batch.

ACE-031 at a glance

• Compound: ACE-031
• Also known as: ramatercept
• Class: soluble activin receptor fusion protein
• Size: 1mg
• Purity: 99% or higher, verified by first- and third-party testing
• Use: laboratory research only

How we test each batch

Every batch is tested before it goes on sale. Identity is checked by mass spectrometry, and purity by HPLC, with a target of 99% or higher.

Each container is labeled with the product, the amount and the batch number. Email us that number and we’ll send the certificate of analysis for your batch.

Storage and shelf life

Keep the container sealed at room temperature, away from heat, moisture and sunlight. Label the container with the opening date. It saves guesswork later.

Working with it safely

Treat it as a lab chemical. Gloves and safety glasses are the minimum, and a clean, uncluttered workspace cuts down on mix-ups.

Store prepared solutions apart from untouched stock, and record who mixed what and when.

Other compounds to look at

• Taltirelin: Taltirelin is a synthetic TRH analog developed by Tanabe Seiyaku in Japan.
• MK-677 + Zinc + 5-HTP + Vitamin B6 + TUDCA Capsules, combining MK-677, 5-HTP, B-6 and TUDCA
• IGF-1 LR3: IGF-1 LR3 is an 83-amino-acid analog of IGF-1 with an arginine swap at position 3 and a 13-amino-acid extension.
• Myostatin Propeptide: Myostatin propeptide is the N-terminal prodomain that the cell cuts off when it makes myostatin (GDF-8).
• Sermorelin: Sermorelin is GHRH(1-29), the first 29 amino acids of growth hormone releasing hormone.

For the wider range, visit our growth hormone peptides sections.

How it compares

Ipamorelin: Ipamorelin is a pentapeptide growth hormone secretagogue developed by Novo Nordisk. It acts on the ghrelin receptor and releases GH selectively, with little effect on cortisol or prolactin.

KP-102: KP-102 is the development code for pralmorelin, the peptide better known as GHRP-2. It’s a synthetic hexapeptide, D-Ala-D-2Nal-Ala-Trp-D-Phe-Lys-NH2, that acts on the ghrelin receptor.

Myostatin Propeptide: Myostatin propeptide is the N-terminal prodomain that the cell cuts off when it makes myostatin (GDF-8). After cleavage it stays wrapped around the active myostatin dimer and keeps it inactive.

Common questions about ACE-031

How should I store it?

Follow the storage section above. In short: cold and dark for freeze-dried vials, room temperature and dry for capsules, tablets, powders and liquids, unless the label says otherwise.

Is ACE-031 in stock?

Yes. It’s in stock and ships from our warehouse after your order clears.

Does it come with a certificate of analysis?

Yes. Every batch is tested, and we’ll email the certificate of analysis for your batch number on request.

Can it be used in people or animals?

No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.

Buy ACE-031 from Pure Rawz

Order ACE-031 now for $162.31. It’s in stock, and checkout takes about two minutes.

Need more for the same project? Have a look at our growth hormone peptides and research peptides.

For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.