Description
Our DHF Free Base is a flavone TrkB agonist, supplied as a powder. Every batch is tested for 99% purity or better, and it’s sold for laboratory research only.
DHF Free Base explained
4′-Dimethylamino-7,8-dihydroxyflavone (eutropoflavin) is a synthetic derivative of 7,8-DHF. The dimethylamino group was added to make it more potent at the TrkB receptor.
It’s sold here as the free base.
Mechanism of action
Eutropoflavin activates the TrkB receptor more strongly than 7,8-DHF, switching on the same BDNF-type signaling that supports neuron survival.
The dimethylamino group also improves how much reaches the brain.
Published DHF Free Base research
Liu and colleagues reported in 2010 that it was a stronger TrkB agonist than 7,8-DHF and had antidepressant-like effects in mice.
Data beyond that are limited.
To read the original papers, start with this PubMed search for 4-DMA-7,8-DHF.
Options and prices
This listing is 1g of powder for $32.99.
Powder suits labs that want to make their own solutions or capsules. Weigh it on a milligram scale.
How labs use it
Cognition studies often test a compound in a deficit model, for example after sleep loss, stress or a drug that impairs memory, because effects are easier to see there than in healthy animals.
Start with the smallest size to confirm solubility and handling, then scale up once the protocol is set.
Cognition studies mostly score behavior, such as maze learning or object recognition. Many also measure something in brain tissue afterwards, like BDNF or acetylcholine.
DHF Free Base specifications
- Compound: 4-DMA-7,8-DHF
- Also known as: eutropoflavin
- Class: flavone TrkB agonist
- Forms: powder
- Size: 1g
- Purity: 99% or higher, verified by first- and third-party testing
- Use: laboratory research only
How we test each batch
Every batch is tested before it goes on sale. Identity is checked by mass spectrometry, and purity by HPLC, with a target of 99% or higher.
Each container is labeled with the product, the amount and the batch number. Email us that number and we’ll send the certificate of analysis for your batch.
Keeping it fresh
Store capsules, tablets and powder in a cool, dry place out of direct light, with the lid closed tight. Write the date you opened or mixed it on the label, so anyone else in the lab knows how old it is.
Safe handling
Handle it the way you’d handle any research chemical: gloves, eye protection and a clean bench. Don’t eat or drink where you work with it.
Keep it out of reach of anyone who isn’t trained, and dispose of used syringes, vials and wipes according to your lab’s waste rules.
What you’ll need
- a milligram scale, since powder has to be weighed
- a suitable solvent if you’re making your own solution, such as DMSO or propylene glycol
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For the wider range, visit our nootropics sections.
Alternatives to consider
GTS-21 HCl: GTS-21 (DMXB-A) is a partial agonist at alpha7 nicotinic acetylcholine receptors. It’s a derivative of anabaseine, a toxin found in marine worms.
Caffeine Anhydrous: Caffeine anhydrous is caffeine with the water removed, a fine white powder. Caffeine is a methylxanthine found in coffee, tea and cacao.
DHF Free Base FAQ
Does it come with a certificate of analysis?
Yes. Every batch is tested, and we’ll email the certificate of analysis for your batch number on request.
Can it be used in people or animals?
No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.
How should I store it?
Follow the storage section above. In short: cold and dark for freeze-dried vials, room temperature and dry for capsules, tablets, powders and liquids, unless the label says otherwise.
Is DHF Free Base in stock?
Yes. It’s in stock and ships from our warehouse after your order clears.
Buy DHF Free Base online
Ready to order? DHF Free Base starts at $32.99 and ships from stock. Add it to your cart and you’re done.
Need more for the same project? Have a look at our nootropics.
For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.
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