Sulbutiamine

Description

Pure Rawz Sulbutiamine is a lipophilic thiamine derivative. Every batch is tested for 99% purity or better, and it’s sold for laboratory research only.

About Sulbutiamine

Sulbutiamine is two modified thiamine (vitamin B1) molecules linked by a disulfide bond. It was developed in Japan in the 1960s to get more thiamine into the brain.

It’s sold in France as Arcalion.

How it acts in research models

Sulbutiamine crosses into the brain easily because it’s fat-soluble, then is reduced back into thiamine. More thiamine supports energy metabolism and acetylcholine and glutamate signaling.

It raises brain thiamine levels more than thiamine itself.

Published Sulbutiamine research

Trials looked at fatigue after infection and in multiple sclerosis, with mixed results.

Rodent studies report effects on memory and on dopamine and glutamate signaling.

For the studies themselves, try this PubMed search.

Sulbutiamine sizes and forms

There are 3 ways to buy it, from $17.47 to $61.76:

• 10g: $17.47
• 20g: $34.41
• 40g: $61.76

How labs use it

Cognition studies often test a compound in a deficit model, for example after sleep loss, stress or a drug that impairs memory, because effects are easier to see there than in healthy animals.

Start with the smallest size to confirm solubility and handling, then scale up once the protocol is set.

Test a range of amounts if you can. Many cognition compounds have an inverted-U response, where too much works worse than a moderate amount.

Sulbutiamine at a glance

• Compound: Sulbutiamine
• Class: lipophilic thiamine derivative
• Options: 3 sizes and forms
• Purity: 99% or higher, verified by first- and third-party testing
• Use: laboratory research only

Purity and batch testing

Every batch is tested before it goes on sale. Identity is checked by mass spectrometry, and purity by HPLC, with a target of 99% or higher.

Each container is labeled with the product, the amount and the batch number. Email us that number and we’ll send the certificate of analysis for your batch.

Keeping it fresh

Store capsules, tablets and powder in a cool, dry place out of direct light, with the lid closed tight. Write the date you opened or mixed it on the label, so anyone else in the lab knows how old it is.

Working with it safely

Handle it the way you’d handle any research chemical: gloves, eye protection and a clean bench. Don’t eat or drink where you work with it.

Keep it out of reach of anyone who isn’t trained, and dispose of used syringes, vials and wipes according to your lab’s waste rules.

Other compounds to look at

• Caffeine Anhydrous: Caffeine anhydrous is caffeine with the water removed, a fine white powder.
• IDRA-21: IDRA-21 is a benzothiadiazine that reduces AMPA receptor desensitization.
• TAK-653 Powder: TAK-653 is an AMPA receptor potentiator from Takeda with very low agonist activity.
• Pramipexole: Pramipexole is a non-ergot dopamine agonist from Boehringer Ingelheim, approved in the US in 1997 as Mirapex for Parkinson’s disease and later for restless legs syndrome.
• PRL-8-53: PRL-8-53 (CAS 51352-88-6) is a methyl benzoate derivative synthesised by Nikolaus Hansl at Creighton University in the 1970s.

For the wider range, visit our nootropics sections.

Similar compounds compared

Agmatine Sulfate: Agmatine is made in the body from arginine and works as a neuromodulator. Agmatine sulfate is the stable salt used in research.

Fladrafinil: Fladrafinil (CRL-40,941, also called fluorafinil) is a bis-fluorinated version of adrafinil, made by Lafon Laboratories in France in the 1970s. Like adrafinil, it’s thought to act partly through conversion to a modafinil-like metabolite.

L-Tetrahydropalmatine (L-THP): L-Tetrahydropalmatine is an alkaloid from Corydalis and Stephania plants, used in Chinese medicine for pain and sleep.

Sulbutiamine FAQ

What forms does it come in?

It comes in 3 sizes, listed in the dropdown on this page.

Is Sulbutiamine in stock?

Yes. It’s in stock and ships from our warehouse after your order clears.

Does it come with a certificate of analysis?

Yes. Every batch is tested, and we’ll email the certificate of analysis for your batch number on request.

Can it be used in people or animals?

No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.

How should I store it?

Follow the storage section above. In short: cold and dark for freeze-dried vials, room temperature and dry for capsules, tablets, powders and liquids, unless the label says otherwise.

Order Sulbutiamine today

Order Sulbutiamine now from $17.47. It’s in stock, and checkout takes about two minutes.

Need more for the same project? Have a look at our nootropics.

For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.