PNC-28

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Description

Buy PNC-28 Peptide Online

PNC-28 is a synthetic peptide derived from the p53 MDM2-binding region and linked to a cell-penetrating sequence. It has primarily been investigated in experimental cancer research.

Product Information

PNC-28 has demonstrated cytotoxic activity against several cancer cell lines and has been studied in animal tumor models. These findings are preclinical and do not establish PNC-28 as a human cancer treatment.

How Does It Work?

PNC-28 contains a p53-derived sequence linked to penetratin, enabling cellular entry. Experimental research suggests that it can interact with membrane-associated targets and induce necrotic cell death in susceptible tumor cells.

Benefits

Cancer-Cell Research

PNC-28 has demonstrated cytotoxic effects against several human cancer cell lines in laboratory experiments.

p53-Pathway Research

The peptide was developed from a region of p53 involved in interaction with MDM2, providing a model for investigating p53-related cancer biology.

Cell-Penetration Research

The penetratin sequence allows investigation of intracellular delivery and cell-penetrating peptide mechanisms.

Tumor-Model Research

Animal studies have examined PNC-28 in tumor models and reported inhibition of tumor growth.

Side Effects

No established human safety profile exists for PNC-28. Cell and animal experiments cannot reliably predict human toxicity or tolerability.

Dosage

No validated human dosage exists for PNC-28. Animal research protocols should not be converted into human dosing instructions.

Where to Buy PNC-28 Peptide

Purerawz does not sell or directly supply PNC-28. Where available, links may direct readers to independent third-party providers through affiliate relationships.

References

PNC-28, a p53-derived peptide that is cytotoxic to cancer cells, blocks pancreatic cancer cell growth in vivo.

PMID: 16688716.

The penetratin sequence in the anticancer PNC-28 peptide causes tumor cell necrosis rather than apoptosis of human pancreatic cancer cells.

PMID: 18931881

Purerawz Disclaimer

Purerawz does not sell, manufacture, stock, dispense, or directly supply any of the products discussed on this website. Purerawz is an independent information and affiliate platform. Where available, links may direct readers to independent third-party suppliers, and Purerawz may receive a commission from qualifying purchases at no additional cost to the reader.

The information on these pages is provided for educational and informational purposes only. Dosage figures may reflect published research protocols or reported community use and should not be interpreted as personalized medical instructions. Research findings, particularly animal and early-stage studies, do not necessarily translate into established human benefits or safety.

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