Mirodenafil

Description

Our Mirodenafil is a PDE5 inhibitor, supplied as tablets and a liquid. Each batch is checked for 99%+ purity. It’s intended for research use only.

Mirodenafil explained

Mirodenafil (SK3530) is a PDE5 inhibitor developed by SK Chemicals in South Korea, where it’s approved for erectile dysfunction.

It’s also been studied in Alzheimer’s models.

How it works

Mirodenafil blocks PDE5, which breaks down cGMP in smooth muscle. With more cGMP, nitric oxide signaling lasts longer and blood vessels relax.

It’s more selective for PDE5 over PDE6 than sildenafil.

Published Mirodenafil research

Paick and colleagues published Korean phase 3 data.

Preclinical work looked at memory in mice.

Like other PDE5 inhibitors, it raises cGMP, which relaxes smooth muscle in blood vessels.

To read the original papers, start with this PubMed search for Mirodenafil.

Choosing your option

It comes in 3 options. Pick one from the dropdown above the cart button:

• Tablets, 50mg per tablet/20ct/1g: $58.42
• Tablets, 50mg per tablet/40ct/2g: $100.62
• Liquid, 30ml/33mg per ml/1000mg: $80.12

Tablets are pressed with a fixed amount per tablet, shown in the size option along with the count.

The liquid comes in a glass dropper bottle at a stated concentration per mL, so every draw is easy to calculate.

Using Mirodenafil in the lab

Researchers use reference compounds to anchor a study: if the known drug gives the expected result, the model is behaving. Then the new compound can be compared against it.

Use the published pharmacology as your starting point and record the exact form, such as the salt or the solution strength.

Use the approved product label or published pharmacology as your reference for expected effects, and note the salt form, since it changes the molecular weight.

Measuring the liquid

At 33mg per mL, every 1mL holds 33mg and every 0.1mL holds 3.3mg. A graduated 1mL dropper or syringe makes those measures accurate.

Mirodenafil specifications

• Compound: Mirodenafil
• Also known as: SK3530
• Class: PDE5 inhibitor
• Forms: tablets and liquid
• Options: 3 sizes and forms
• Purity: 99% or higher, verified by first- and third-party testing
• Use: laboratory research only

Quality and testing

We test each batch for identity and purity before it ships, using HPLC and mass spectrometry, with independent third-party checks on top of our own.

The batch number on the label matches the certificate of analysis. If your lab keeps paperwork on file, ask us for it and we’ll email it over.

Keeping it fresh

Store capsules, tablets and powder in a cool, dry place out of direct light, with the lid closed tight. Store liquids at room temperature with the cap screwed on, away from heat and light.

Note the batch number and the date you opened it in your lab records.

Working with it safely

Wear gloves and eye protection when you open or measure it, and work on a clean surface.

Label everything you prepare, keep it away from food areas, and follow your lab’s rules for disposing of sharps and chemical waste.

Before you start

• a graduated 1mL dropper or syringe for accurate volumes

Often ordered alongside

• Tadalafil: Tadalafil is a PDE5 inhibitor developed by ICOS and Eli Lilly and approved in 2003 as Cialis.
• Amino Tadalafil: Aminotadalafil is a structural analog of tadalafil, with formula C21H18N4O4 and CAS 385769-84-6.
• Vardenafil Citrate: Vardenafil is a phosphodiesterase type 5 inhibitor developed by Bayer and approved in 2003 as Levitra for erectile dysfunction.
• Nebivolol: Nebivolol is a highly beta-1 selective beta blocker, sold as Bystolic for high blood pressure.
• PP-405: PP-405 is a small-molecule compound from Pelage Pharmaceuticals, a UCLA spin-out, developed for hair loss as a topical treatment.

See the rest of our research compounds for more options.

Similar compounds compared

Propranolol: Propranolol was the first beta blocker to succeed clinically, developed by James Black at ICI in the 1960s. Black received the 1988 Nobel Prize partly for this work.

EPO (Erythropoietin): Erythropoietin is a 165-amino-acid glycoprotein hormone made mainly in the kidney. It tells the bone marrow to produce red blood cells.

Mirodenafil questions

Is Mirodenafil in stock?

Yes. It’s in stock and ships from our warehouse after your order clears.

Does it come with a certificate of analysis?

Yes. Every batch is tested, and we’ll email the certificate of analysis for your batch number on request.

Can it be used in people or animals?

No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.

How should I store it?

Follow the storage section above. In short: cold and dark for freeze-dried vials, room temperature and dry for capsules, tablets, powders and liquids, unless the label says otherwise.

What forms does it come in?

Tablets and a liquid. Pick the one you want from the dropdown on this page.

Order Mirodenafil today

Mirodenafil is in stock from $58.42. Choose your option, add it to the cart and check out in a couple of minutes.

Need more for the same project? Have a look at our research compounds.

For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.