EPO (Erythropoietin)

Description

EPO is an erythropoiesis-stimulating glycoprotein hormone, sold by Pure Rawz for laboratory research. Every batch is tested for 99% purity or better, and it’s sold for laboratory research only.

About EPO

Erythropoietin is a 165-amino-acid glycoprotein hormone made mainly in the kidney. It tells the bone marrow to produce red blood cells.

Recombinant EPO (epoetin alfa) has been approved since 1989 for anemia in kidney disease. It’s also one of the best-known substances on the WADA prohibited list.

How it works

EPO binds the EPO receptor on red blood cell precursors and activates JAK2-STAT5 signaling. That keeps the precursors alive and pushes them to divide and mature.

The receptor also sits on other tissues, and a second receptor complex with the beta common receptor is thought to explain the protective effects seen in nerve and heart models.

What studies say about EPO

Eschbach and colleagues reported in the New England Journal of Medicine in 1987 that recombinant EPO corrected anemia in dialysis patients.

Later research looked at EPO’s effects outside the blood, including neuroprotection and tissue protection in injury models, which led to non-erythropoietic derivatives such as ARA-290.

To read the original papers, start with this PubMed search for EPO.

Choosing your option

It comes in one option (3000iu), priced at $42.98.

Using EPO in the lab

These are approved-drug reference compounds sold for research, such as receptor and enzyme studies, assay development and comparison against newer molecules. Their pharmacology is well documented, which makes them useful as positive controls.

Because their actions are well known, labs often use them to check that an assay or model is working before testing an unknown compound.

Endpoints follow the drug’s known pharmacology: blood pressure and heart rate for cardiovascular compounds, receptor binding or enzyme activity for assay work, or the specific tissue response the drug is known for.

EPO product details

• Compound: EPO
• Also known as: erythropoietin, epoetin
• CAS number: 11096-26-7
• Molar mass: about 30.4 kDa (glycosylated)
• Structure: 165 amino acids with four glycan chains
• Class: erythropoiesis-stimulating glycoprotein hormone
• Size: 3000iu
• Purity: 99% or higher, verified by first- and third-party testing
• Use: laboratory research only

Purity and batch testing

We test each batch for identity and purity before it ships, using HPLC and mass spectrometry, with independent third-party checks on top of our own.

The batch number on the label matches the certificate of analysis. If your lab keeps paperwork on file, ask us for it and we’ll email it over.

Storage and shelf life

Keep the container sealed at room temperature, away from heat, moisture and sunlight. Write the date you opened or mixed it on the label, so anyone else in the lab knows how old it is.

Handling notes

Handle it the way you’d handle any research chemical: gloves, eye protection and a clean bench. Don’t eat or drink where you work with it.

Keep it out of reach of anyone who isn’t trained, and dispose of used syringes, vials and wipes according to your lab’s waste rules.

Often ordered alongside

• T3 Liothyronine Sodium: Liothyronine is synthetic T3, triiodothyronine, the active form of thyroid hormone.
• Sildenafil: Sildenafil is the first oral PDE5 inhibitor, discovered by Pfizer scientists in Sandwich, England, while testing it for angina.
• PP-405: PP-405 is a small-molecule compound from Pelage Pharmaceuticals, a UCLA spin-out, developed for hair loss as a topical treatment.
• Vardenafil Citrate: Vardenafil is a phosphodiesterase type 5 inhibitor developed by Bayer and approved in 2003 as Levitra for erectile dysfunction.
• Minoxidil 5%: Minoxidil is a potassium channel opener developed by Upjohn as a blood pressure drug in the 1970s.

For the wider range, visit our research compounds sections.

Similar compounds compared

Sildenafil: Sildenafil is the first oral PDE5 inhibitor, discovered by Pfizer scientists in Sandwich, England, while testing it for angina. It was approved as Viagra in 1998 and later as Revatio for pulmonary arterial hypertension.

Minoxidil 5%: Minoxidil is a potassium channel opener developed by Upjohn as a blood pressure drug in the 1970s. Patients taking it grew more hair, which led to the topical version, Rogaine.

EPO FAQ

Is EPO in stock?

Yes. It’s in stock and ships from our warehouse after your order clears.

Does it come with a certificate of analysis?

Yes. Every batch is tested, and we’ll email the certificate of analysis for your batch number on request.

Can it be used in people or animals?

No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.

How should I store it?

Follow the storage section above. In short: cold and dark for freeze-dried vials, room temperature and dry for capsules, tablets, powders and liquids, unless the label says otherwise.

Buy EPO from Pure Rawz

EPO is in stock at $42.98. Add it to the cart and check out in a couple of minutes.

Need more for the same project? Have a look at our research compounds and research peptides.

For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.