Description
Our Hydrochlorothiazide is a thiazide diuretic, supplied as tablets. Each batch is checked for 99%+ purity. It’s intended for research use only.
What is Hydrochlorothiazide?
Hydrochlorothiazide, or HCTZ, is a thiazide diuretic introduced in 1959. It’s one of the most prescribed blood pressure drugs in the world.
It’s a small sulfonamide-based molecule.
How it acts in research models
HCTZ blocks the sodium-chloride cotransporter in the distal convoluted tubule of the kidney. More sodium and water leave in the urine, and blood volume and pressure fall.
It reduces calcium loss in urine, the opposite of loop diuretics.
Hydrochlorothiazide research
Trials such as ALLHAT showed thiazide-type diuretics lowered cardiovascular events as well as newer drugs. HCTZ is the standard diuretic in many combination pills.
Research also covers its effects on calcium and on kidney stone risk.
The primary literature is on PubMed. Here’s a search to start from.
Options and prices
This listing is a bottle of 30 tablets, 25mg each, for $29.99.
Each tablet holds the same measured amount, which the size option spells out.
How labs use it
Researchers use reference compounds to anchor a study: if the known drug gives the expected result, the model is behaving. Then the new compound can be compared against it.
Use the published pharmacology as your starting point and record the exact form, such as the salt or the solution strength.
Endpoints follow the drug’s known pharmacology: blood pressure and heart rate for cardiovascular compounds, receptor binding or enzyme activity for assay work, or the specific tissue response the drug is known for.
Hydrochlorothiazide specifications
- Compound: Hydrochlorothiazide
- Also known as: HCTZ
- CAS number: 58-93-5
- Molecular formula: C7H8ClN3O4S2
- Molar mass: 297.7 g/mol
- Structure: benzothiadiazine
- Class: thiazide diuretic
- Forms: tablets
- Size: 25mg per tablet/30ct
- Purity: 99% or higher, verified by first- and third-party testing
- Use: laboratory research only
How we test each batch
We test each batch for identity and purity before it ships, using HPLC and mass spectrometry, with independent third-party checks on top of our own.
The batch number on the label matches the certificate of analysis. If your lab keeps paperwork on file, ask us for it and we’ll email it over.
How to store Hydrochlorothiazide
Keep the container sealed at room temperature, away from heat, moisture and sunlight. Label the container with the opening date. It saves guesswork later.
Working with it safely
Handle it the way you’d handle any research chemical: gloves, eye protection and a clean bench. Don’t eat or drink where you work with it.
Keep it out of reach of anyone who isn’t trained, and dispose of used syringes, vials and wipes according to your lab’s waste rules.
What you’ll need
- nothing extra for capsules or tablets, as each unit is pre-measured
- a dry, sealed container if you split a bottle between projects
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See the rest of our research compounds for more options.
Similar compounds compared
EPO (Erythropoietin): Erythropoietin is a 165-amino-acid glycoprotein hormone made mainly in the kidney. It tells the bone marrow to produce red blood cells.
Vardenafil Citrate: Vardenafil is a phosphodiesterase type 5 inhibitor developed by Bayer and approved in 2003 as Levitra for erectile dysfunction. It’s structurally close to sildenafil, with a different ring system that makes it more potent at PDE5.
Hydrochlorothiazide questions
Is Hydrochlorothiazide in stock?
Yes. It’s in stock and ships from our warehouse after your order clears.
Does it come with a certificate of analysis?
Yes. Every batch is tested, and we’ll email the certificate of analysis for your batch number on request.
Can it be used in people or animals?
No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.
How should I store it?
Follow the storage section above. In short: cold and dark for freeze-dried vials, room temperature and dry for capsules, tablets, powders and liquids, unless the label says otherwise.
Buy Hydrochlorothiazide online
Order Hydrochlorothiazide now for $29.99. It’s in stock, and checkout takes about two minutes.
Need more for the same project? Have a look at our research compounds.
For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.
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