4F-Phenibut Free Base

Description

Pure Rawz 4F-Phenibut Free Base is a fluorinated GABA-B agonist, available as a powder. Every batch is tested for 99% purity or better, and it’s sold for laboratory research only.

4F-Phenibut Free Base explained

4F-Phenibut is 4-fluorophenibut, also called F-phenibut or CGP-11130. It’s phenibut with a fluorine atom on the phenyl ring, which makes it a stronger GABA-B agonist.

It’s sold here as the HCl salt and as the free base.

Mechanism of action

4F-Phenibut activates GABA-B receptors, which slows neuron firing by opening potassium channels and closing calcium channels. It’s thought to bind the alpha2-delta subunit of calcium channels much less than phenibut does.

Its effects in animal tests are sedative and anti-anxiety.

What studies say about 4F-Phenibut Free Base

Ciba-Geigy first made it as a research compound. Studies report it binds GABA-B receptors more strongly than phenibut but less than baclofen.

There are no controlled human studies.

To read the original papers, start with this PubMed search for 4F-Phenibut.

Options and prices

This listing is 10g of powder for $88.55.

Powder suits labs that want to make their own solutions or capsules. Weigh it on a milligram scale.

Using 4F-Phenibut Free Base in the lab

Nootropic research usually uses memory and learning tests in rodents, such as maze tasks, object recognition or fear conditioning, along with markers like BDNF or receptor binding.

Behavioral tests are sensitive to handling and time of day, so labs keep both constant and score results blind. A vehicle group run on the same day is the most useful control.

Test a range of amounts if you can. Many cognition compounds have an inverted-U response, where too much works worse than a moderate amount.

4F-Phenibut Free Base specifications

• Compound: 4F-Phenibut
• Also known as: F-phenibut, CGP-11130
• CAS number: 52237-19-1 (base)
• Molecular formula: C10H12FNO2
• Molar mass: 197.2 g/mol (base)
• Structure: 4-amino-3-(4-fluorophenyl)butanoic acid
• Class: fluorinated GABA-B agonist
• Forms: powder
• Size: 10g
• Purity: 99% or higher, verified by first- and third-party testing
• Use: laboratory research only

Purity and batch testing

We test each batch for identity and purity before it ships, using HPLC and mass spectrometry, with independent third-party checks on top of our own.

The batch number on the label matches the certificate of analysis. If your lab keeps paperwork on file, ask us for it and we’ll email it over.

Keeping it fresh

Keep the container sealed at room temperature, away from heat, moisture and sunlight. Label the container with the opening date. It saves guesswork later.

Working with it safely

Handle it the way you’d handle any research chemical: gloves, eye protection and a clean bench. Don’t eat or drink where you work with it.

Keep it out of reach of anyone who isn’t trained, and dispose of used syringes, vials and wipes according to your lab’s waste rules.

Supplies to have on hand

• a milligram scale, since powder has to be weighed
• a suitable solvent if you’re making your own solution, such as DMSO or propylene glycol

Other compounds to look at

• Hydrafinil: 9-Fluorenol (hydrafinil) is fluorene with a hydroxyl at the 9 position.
• Neuro Bundle, combining Semax, Selank and Pinealon
• Phenylpiracetam Hydrazide: Phenylpiracetam hydrazide, also sold as fonturacetam hydrazide, is phenylpiracetam with the amide group swapped for a hydrazide.
• Nooglutyl: Nooglutyl (ONK-10, CAS 112193-35-8) is a Russian nootropic made from glutamic acid and 5-hydroxynicotinic acid.
• IQ Plus, a brain multi-nutrient capsule formula

See the rest of our nootropics for more options.

Similar compounds compared

Piracetam: Piracetam (2-oxo-1-pyrrolidineacetamide) was the first racetam, made by UCB in Belgium in the 1960s. Corneliu Giurgea coined the word nootropic to describe it.

Hydrafinil: 9-Fluorenol (hydrafinil) is fluorene with a hydroxyl at the 9 position. It’s a weak dopamine reuptake inhibitor.

Common questions about 4F-Phenibut Free Base

How should I store it?

Follow the storage section above. In short: cold and dark for freeze-dried vials, room temperature and dry for capsules, tablets, powders and liquids, unless the label says otherwise.

Is 4F-Phenibut Free Base in stock?

Yes. It’s in stock and ships from our warehouse after your order clears.

Does it come with a certificate of analysis?

Yes. Every batch is tested, and we’ll email the certificate of analysis for your batch number on request.

Can it be used in people or animals?

No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.

Buy 4F-Phenibut Free Base from Pure Rawz

Ready to order? 4F-Phenibut Free Base starts at $88.55 and ships from stock. Add it to your cart and you’re done.

Need more for the same project? Have a look at our nootropics.

For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.