Description
The Mass Construction 2.0 from Pure Rawz puts MK-677, 4-Andro, LGD-4033 and YK-11 together in a liquid. Each batch is checked for 99%+ purity. It’s intended for research use only.
Inside Mass Construction 2.0
MK-677
MK-677 (ibutamoren) is an orally active, nonpeptide growth hormone secretagogue developed by Merck. It mimics ghrelin at the GHS-R1a receptor, raising growth hormone and IGF-1. It’s often sold next to SARMs, but it isn’t one.
MK-677 binds GHS-R1a, the same receptor as ghrelin and the GHRP peptides, in the pituitary and hypothalamus. That boosts the size of natural GH pulses and lifts IGF-1 from the liver.
4-Andro
4-Andro is 4-androstene-3-beta-ol-17-one, a prohormone that converts to testosterone. It’s closely related to androstenedione.
4-Andro is converted to testosterone by 17-beta-HSD. Because testosterone can aromatize, some of it becomes estradiol.
LGD-4033
LGD-4033 (ligandrol, also coded VK5211) is a nonsteroidal SARM discovered by Ligand Pharmaceuticals and later licensed to Viking Therapeutics. It binds the androgen receptor with high affinity and, in animal models, acts strongly on muscle and bone while sparing the prostate.
Like other SARMs, LGD-4033 binds the androgen receptor and the receptor complex moves into the nucleus to switch on androgen-responsive genes. Its binding is unusually tight, with a reported Ki around 1 nanomolar.
YK-11
YK-11 is a steroidal compound built on a dihydrotestosterone backbone, first described by Japanese researchers in 2011. It’s usually sold next to SARMs, but it’s a steroid and only a partial agonist at the androgen receptor.
YK-11 binds the androgen receptor but doesn’t trigger the full shape change that DHT does, so it activates only part of the usual gene program. That’s why it’s called a partial agonist.
Why Mass Construction 2.0 combines these compounds
Labs pair these compounds because each works through a different pathway, so combining them covers more of the system in one study. A fixed mix also means one product, one label and no drift between separate containers.
Mass Construction 2.0 research background
Nass and colleagues ran a two-year trial in healthy older adults, published in the Annals of Internal Medicine in 2008. MK-677 raised GH and IGF-1 to levels seen in young adults and increased fat-free mass, with rises in fasting glucose noted.
Research on this family, including studies on androstenedione by King and colleagues in JAMA (1999), found that much of the material turned into estrogen as well as testosterone.
A phase 1 study by Basaria and colleagues, published in the Journals of Gerontology in 2013, gave LGD-4033 to 76 healthy young men for 21 days. Lean body mass rose with the dose, and the study also reported dose-related drops in HDL cholesterol and testosterone.
For the original studies, start with this PubMed search for MK-677, 4-Andro and LGD-4033.
Options and prices
It comes in one option (Liquid, 4 x 30ml (7000mg total)), priced at $649.99.
The liquid comes in a glass dropper bottle at a stated concentration per mL, so every draw is easy to calculate.
Using Mass Construction 2.0 in the lab
Labs comparing SARMs usually match exposure time and measure the same panel across compounds: muscle and prostate weight in rodents, plus hormone and lipid markers. That tissue-selectivity ratio is what SARM research is built around.
Liquids make small, even measurements easy, while capsules and tablets suit studies that need a fixed amount per unit.
The classic rodent readout compares levator ani muscle weight with prostate weight, which shows how tissue-selective a compound is. Body composition scans and hormone blood work usually sit alongside it.
Mass Construction 2.0 at a glance
- Contains: MK-677, 4-Andro, LGD-4033 and YK-11
- Forms: liquid
- Size: 4 x 30ml (7000mg total)
- Purity: 99% or higher, verified by first- and third-party testing
- Use: laboratory research only
How we test each batch
We test each batch for identity and purity before it ships, using HPLC and mass spectrometry, with independent third-party checks on top of our own.
The batch number on the label matches the certificate of analysis. If your lab keeps paperwork on file, ask us for it and we’ll email it over.
How to store Mass Construction 2.0
Store liquids at room temperature with the cap screwed on, away from heat and light. Label the container with the opening date. It saves guesswork later.
Handling notes
Wear gloves and eye protection when you open or measure it, and work on a clean surface.
Label everything you prepare, keep it away from food areas, and follow your lab’s rules for disposing of sharps and chemical waste.
What you’ll need
- a graduated 1mL dropper or syringe for accurate volumes
Often ordered alongside
- RAD-140 + MK-677 + YK-11 Value Pack, combining RAD-140, MK-677 and YK-11
- S4 Andarine + Ostarine Stack (MK-2866), combining S4 Andarine and MK-2866
- Olympian Quad Capsules: Olympian Quad puts four compounds in one capsule: arimistane 40mg, 1-Andro 80mg, 4-Andro 80mg and MK-677 40mg, for 240mg per capsule and 30 capsules per bottle.
- RAD-150 (TLB 150): RAD-150 (also sold as TLB-150) is an ester of RAD-140.
- Super Mass Bombs: Super Mass Bombs packs have 5,000mg creatine monohydrate, 2,500mg beta-alanine and 2,000mg L-carnitine tartrate.
For the wider range, visit our SARMs sections.
Mass Construction 2.0 questions
How should I store it?
Follow the storage section above. In short: cold and dark for freeze-dried vials, room temperature and dry for capsules, tablets, powders and liquids, unless the label says otherwise.
Is Mass Construction 2.0 in stock?
Yes. It’s in stock and ships from our warehouse after your order clears.
Does it come with a certificate of analysis?
Yes. Every batch is tested, and we’ll email the certificate of analysis for your batch number on request.
Can it be used in people or animals?
No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.
What’s in Mass Construction 2.0?
MK-677, 4-Andro, LGD-4033 and YK-11. The section above covers each one.
Buy Mass Construction 2.0 online
Order Mass Construction 2.0 now for $649.99. It’s in stock, and checkout takes about two minutes.
Need more for the same project? Have a look at our SARMs.
For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.
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