Description
TP-508 is a thrombin-derived regenerative peptide, sold by Pure Rawz for laboratory research. It’s tested to 99% purity or higher and sold strictly for lab research.
TP-508 explained
TP-508, also called Chrysalin, is a 23-amino-acid peptide taken from a non-enzyme region of human thrombin. It was developed by OrthoLogic.
It doesn’t clot blood. It mimics the part of thrombin that binds cells and signals for repair.
How it acts in research models
TP-508 binds a non-proteolytically activated thrombin receptor on cells such as fibroblasts and endothelial cells. That raises nitric oxide signaling and recruits cells involved in repair.
Researchers also study it for protecting blood vessels after radiation injury.
TP-508 research
Phase 1 and 2 trials looked at TP-508 for diabetic foot ulcers and for wrist fractures. Animal studies reported faster fracture and wound healing and better blood vessel growth.
Development stopped after phase 3 fracture results were mixed.
The primary literature is on PubMed. Here’s a search to start from.
TP-508 sizes and forms
It comes in one option, priced at $399.99.
Using TP-508 in the lab
Repair peptide research mostly uses injury models: tendon or ligament damage, skin wounds, gut lining injury or muscle strain. Healing time, tissue strength and histology are the usual endpoints.
Because injury models vary a lot between animals, labs use larger groups and blinded scoring. A sham-injury group helps separate the peptide’s effect from normal healing.
Pick your time points before the study starts. Repair happens in phases, and the phase you sample changes what you see.
TP-508 specifications
- Compound: TP-508
- Also known as: Chrysalin, rusalatide acetate
- Molar mass: about 2,300 g/mol
- Structure: 23 amino acids (thrombin 508-530)
- Class: thrombin-derived regenerative peptide
- Purity: 99% or higher, verified by first- and third-party testing
- Use: laboratory research only
How we test each batch
We test each batch for identity and purity before it ships, using HPLC and mass spectrometry, with independent third-party checks on top of our own.
The batch number on the label matches the certificate of analysis. If your lab keeps paperwork on file, ask us for it and we’ll email it over.
Keeping it fresh
Keep the container sealed at room temperature, away from heat, moisture and sunlight. Write the date you opened or mixed it on the label, so anyone else in the lab knows how old it is.
Working with it safely
Wear gloves and eye protection when you open or measure it, and work on a clean surface.
Label everything you prepare, keep it away from food areas, and follow your lab’s rules for disposing of sharps and chemical waste.
Often ordered alongside
- KPV (Lysine-Proline-Valine): KPV is the tripeptide lysine-proline-valine, the C-terminal end of alpha-melanocyte stimulating hormone.
- ARA-290: ARA-290 (cibinetide) is an 11-amino-acid peptide based on a region of erythropoietin.
- GHK-Cu Copper Peptide: GHK-Cu is the tripeptide glycyl-histidyl-lysine bound to a copper ion.
- Thymosin Beta-4 Fragment 1-4: Thymosin beta-4 fragment 1-4 is Ac-Ser-Asp-Lys-Pro, also called Ac-SDKP or goralatide.
- TB-500 Fragment 17-23: TB-500 Frag 17-23 is a seven-amino-acid piece of thymosin beta-4, Leu-Lys-Lys-Thr-Glu-Thr-Gln, usually with an acetyl cap on the first residue.
See the rest of our healing and recovery peptides for more options.
Similar compounds compared
BPC-157: BPC-157 is a 15-amino-acid peptide based on a fragment of body protection compound, a protein first found in gastric juice. It’s one of the most widely studied research peptides, almost entirely in rodents.
N-Acetyl Larazotide: Larazotide acetate is an eight-amino-acid peptide, GGVLVQPG, based on a sequence from zonula occludens toxin. It was developed by Alba Therapeutics and later 9 Meters Biopharma for celiac disease.
TB-500 Fragment 17-23: TB-500 Frag 17-23 is a seven-amino-acid piece of thymosin beta-4, Leu-Lys-Lys-Thr-Glu-Thr-Gln, usually with an acetyl cap on the first residue. Positions 17 to 23 are the stretch of the full protein that binds actin.
TP-508 FAQ
Does it come with a certificate of analysis?
Yes. Every batch is tested, and we’ll email the certificate of analysis for your batch number on request.
Can it be used in people or animals?
No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.
How should I store it?
Follow the storage section above. In short: cold and dark for freeze-dried vials, room temperature and dry for capsules, tablets, powders and liquids, unless the label says otherwise.
Is TP-508 in stock?
Yes. It’s in stock and ships from our warehouse after your order clears.
Buy TP-508 from Pure Rawz
Order TP-508 now for $399.99. It’s in stock, and checkout takes about two minutes.
Need more for the same project? Have a look at our healing and recovery peptides and research peptides.
For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.
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