Description
What is Silymarin 98% + TUDCA Stack?
The Silymarin 98% + TUDCA stack is being investigated for its potential to improve liver protection through synergistic actions. In experimental conditions, the combination may offer more comprehensive support for liver cells. It may help defend against different types of injury, encourage cell regeneration, and promote potential liver detox. This has drawn interest in various studies. These studies may lead to better understanding of liver function in test subjects.
This blend contains:
- 100mg of Silymarin 98% and 50mg of TUDCA, totaling 150mg per capsule.
- Available in 2 variants: 100 capsules (15,000mg total) and 200 capsules (30,000mg total).
What is Silymarin?
From milk thistles, silymarin has powerful antioxidant effects. Research shows it protects liver cells from oxidative stress and toxins. This protection aims to preserve liver function. Research suggests that silymarin may promote liver tissue regeneration and reduce inflammation. Due to these properties, it is commonly studied as a liver support supplement. [R]
| CAS | 65666-07-1 |
| Molar Mass | 482.44 g/mol |
| Chemical Formula | C25H22O10 |
| IUPAC Name | 3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one |
How does Silymarin or milk thistle work?
Ancient people have long used silymarin as an herbal remedies. The flavonolignan from’milk thistle’ seeds (Silybum marianum) protects the liver. Silymarin is a combination of three flavonolignans: silybin, silidianin, and silychristine. Medically, silymarin may potentially treat hepatitis. Research has also examined alcoholic liver problems and acute and chronic viral cirrhosis. Furthermore, investigations suggest that it is effective against a variety of malignancies. Hepatotoxins injure livers. They injure liver cells by attaching to receptor sites on membranes. Silymarin works by blocking hepatotoxins from binding to these receptor sites [R].
Although Silymarin shows a lot of potential, further research is needed. Its impact on liver disease, healthy liver function & other conditions still needs to be determined. This research will help establish the recommended silymarin dosages.
Potential effects of silymarin
- It potentially aids in lowering oxidative stress in the liver [R]
- Potentially strengthens liver cell outer membranes [R]
- It may potentially enhance protein synthesis [R]
- Potential treatment for liver cancer. [R]
- It potentially exhibits anti-inflammatory effects. [R]
- It may help prevent progression of liver disease (liver fibrosis) [R]
What is TUDCA?
Tauroursodeoxycholic acid, or TUDCA, is a naturally occurring bile acid. It can improve liver function by increasing bile flow and reducing hepatocyte stress. TUDCA may help preserve cellular integrity by reducing endoplasmic reticulum stress. This stress, if left untreated, can cause liver damage.[R]
| CAS | 14605-22-2 |
| Molar Mass | 499.7 g/mol |
| Chemical Formula | C26H45NO6S |
| IUPAC Name | 2-[[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid |
How does TUDCA work?
Initially considered to be detergent molecules with an important role in lipid digestion. Bile acids have proven to be important in a variety of biological processes. Specifically, bile acids act as regulatory molecules. They interact with many cellular receptors to modulate important signaling pathways [R].
Potential effects of TUDCA:
- It potentially prevent the buildup of toxic bile acids in the liver. [R]
- It potentially protects cells from damage and boost their function. [R]
- It has a potential neuroprotective property. [R]
- It might aid in preventing damage to other tissues, including liver cells[R]
- It potentially maintain cellular energy levels and function [R]
Disclaimer
This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with the appropriate IRB oversight. All preclinical research must be conducted with IACUC following the AWA guidelines.
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