HCG (Human Chorionic Gonadotropin)

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Description

HCG (Human Chorionic Gonadotropin)

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Human chorionic gonadotropin (hCG) is a naturally occurring glycoprotein hormone with biological activity similar to luteinizing hormone (LH). It plays a central role in pregnancy and has also been used clinically in selected male and female reproductive applications.

In males, hCG can stimulate Leydig cells to produce testosterone. In females, it can trigger ovulation under appropriately supervised fertility protocols.

Product Information

hCG binds primarily to LH/hCG receptors in the gonads. This makes it particularly useful for stimulating gonadal steroid production.

Clinical applications include selected cases of hypogonadotropic hypogonadism in males and induction of ovulation following appropriate fertility treatment.

How Does It Work?

hCG mimics LH at the LH/hCG receptor. In males, this stimulates Leydig cells and promotes testosterone production. In females, hCG can trigger final follicular maturation and ovulation after appropriate ovarian stimulation.

Benefits

Stimulates Testosterone Production

hCG directly stimulates Leydig cells, providing a mechanism for increasing endogenous testicular testosterone production in appropriate cases of gonadotropin deficiency.

Supports Male Fertility

Unlike exogenous testosterone, which can suppress LH/FSH signaling, hCG can stimulate the testes directly. It is therefore used in selected fertility-treatment protocols.

Triggers Ovulation

hCG is used in reproductive medicine to mimic the LH surge and trigger final oocyte maturation in appropriately prepared patients.

Well-Established Hormonal Activity

Unlike many research peptides, hCG has decades of clinical experience and regulatory history. Its pharmacology and reproductive effects are comparatively well characterized.

Side Effects

Potential adverse effects include injection-site reactions, headache, edema, mood changes, gynecomastia, acne, increased estradiol, and fluid retention. In females, ovarian hyperstimulation is a clinically important risk in fertility treatment.

Dosage

FDA/DailyMed labeling describes several clinical regimens depending on the indication. For selected cases of male hypogonadotropic hypogonadism, labeled regimens include 500–1,000 IU three times weekly for three weeks followed by the same dose twice weekly for three weeks, with other higher-dose regimens also described.

For ovulation induction following appropriate menotropin treatment, labeling describes 5,000–10,000 IU as a single dose following the final menotropin dose.

Where to Buy HCG

Purerawz does not sell or directly supply hCG. Prescription/clinical hCG should be sourced through legitimate healthcare and pharmacy channels.

References

1. NOVAREL (chorionic gonadotropin) Prescribing Information. DailyMed.
DailyMed — Novarel
2. Dwyer AA, et al. Current landscape of fertility induction in males with hypogonadotropic hypogonadism. 2024 review.
PMC — Fertility Induction Review

Disclaimer

Purerawz does not sell, manufacture, stock, dispense, or directly supply any of the products discussed on this website. Purerawz is an independent information and affiliate platform. Where available, links may direct readers to independent third-party providers, and Purerawz may receive a commission from qualifying purchases at no additional cost to the reader.

The information is educational only.

Additional information

Strength

10000IU, 2000IU, 5000IU

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