Description
NSI-189 Phosphate
Buy NSI-189 Phosphate Online
NSI-189 Phosphate is an experimental neurogenic compound investigated for its potential effects on hippocampal function, cognition, and depressive symptoms.
Product Information
NSI-189 was developed as a small-molecule compound designed to promote neurogenesis. Human clinical studies have investigated the phosphate salt in major depressive disorder.
How Does It Work?
NSI-189 has been investigated for its ability to influence neurogenesis and hippocampal function. Its precise molecular mechanism remains incompletely defined.
Benefits
Strong Neurogenesis Research Interest
NSI-189 was developed specifically around the concept of promoting neuronal growth and hippocampal neurogenesis. This makes it particularly interesting for research into brain structure and function.
Depression Research Interest
Phase 1B and phase 2 clinical studies investigated NSI-189 in people with major depressive disorder. Some analyses suggested potential benefits in selected patient groups, although results have not established it as an approved antidepressant.
Cognitive Research
Because the hippocampus plays a central role in memory and learning, NSI-189 has generated interest in cognitive function. Research has explored whether changes in hippocampal biology could translate into measurable cognitive effects.
Hippocampal-Function Research
NSI-189 provides a research tool for studying compounds designed to influence hippocampal structure and neuroplasticity rather than simply modifying conventional neurotransmitter systems.
Side Effects
Clinical trials generally reported NSI-189 as reasonably well tolerated, but adverse effects included headache, nausea, dizziness, fatigue, and other nonspecific symptoms.
Dosage
Human clinical studies investigated NSI-189 phosphate at 40 mg/day and higher divided-dose regimens, depending on the study. The phosphate salt studied clinically should not automatically be treated as equivalent to other NSI-189 formulations.
Where to Buy NSI-189 Phosphate
Purerawz does not sell or directly supply NSI-189 Phosphate. Where available, links may direct readers to independent third-party providers through affiliate relationships.
References
- Papakostas GI, et al. A phase 2, double-blind, placebo-controlled study of NSI-189 phosphate, a neurogenic compound, among outpatients with major depressive disorder. Mol Psychiatry. 2020;25:1569–1579. PubMed — PMID: 30626911
- A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189. PubMed — PMID: 26643541
Disclaimer
Purerawz does not sell, manufacture, stock, dispense, or directly supply any of the products discussed on this website. Purerawz is an independent information and affiliate platform. Where available, links may direct readers to independent third-party providers, and Purerawz may receive a commission from qualifying purchases at no additional cost to the reader.
The information is for educational and informational purposes only. Dosage figures may reflect published research, historical clinical protocols, or reported market practices and should not be interpreted as personalized medical instructions.
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